SirTLab company was founded by Mr. Boaz Misholi, a prominent figure in Israel’s high-tech industry, and Professor Haim Cohen from Bar-Ilan University in Israel, a world leader in SIRT6 protein research who trained at Harvard Medical School.

In his research on SIRT6, Professor Haim Cohen demonstrated that elevating SIRT6 activity extends the lifespan of mice, with an average extension of about 30%.  This breakthrough results showing that SIRT6, not only extends mice lifespan but also delays the onset of age-related diseases by enhancing DNA repair mechanisms, improving metabolic health, reducing inflammation, preventing frailty, improving short term memory and maintaining young-like physical activity, all contributing to healthy aging (Nature Communications volume 12, Article number: 3208, 2021).

Recognizing the evolving dynamics of human life, where increased longevity often comes with a decline in the quality of life and a rise in chronic diseases, we understand the urgency to develop new strategies. Hence, our focus goes beyond prolonging lifespan; we are dedicated to enhancing healthy longevity.

As we age, the decline in SIRT6 levels across different cells and tissues contributes to a range of age-related pathologies. Recognizing the pivotal role of the SIRT6 protein in diverse mechanisms of aging biology, SirTLab has patented cutting-edge technologies to elevate the specific and direct activity of SIRT6.

This breakthrough empowers us to address various diseases across multiple large markets, fundamentally changing the way we perceive and experience the aging process. Thus, our primary focus lies in enhancing the resilience of the frail elderly population, tackling neurodegeneration, addressing osteoarthritis, managing metabolic syndrome, and promoting longevity.